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Efficacy and safety of Youth-derived Fecal Microbiota Transplantation among adults with Type 1 Diabetes Mellitus: A protocol of pilot randomized controlled trial

2026-02-04 endocrinology Title + abstract only
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BackgroundDysbiosis of gut microbiota plays a key role in type 1 diabetes mellitus (T1DM). Fecal microbiota transplantation represents a novel therapeutic avenue. We hypothesize that youth-derived fecal microbiota transplantation (yFMT) can remodel the gut microecosystem and improve clinical outcomes. This study aims to investigate the efficacy and safety of orally administered yFMT capsules in adults with T1DM. Methods and analysisThis single-center, randomized, double-blind, placebo-controlle...

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