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Model-Based Evaluation of Colorectal Cancer Screening Effectiveness: Three Rounds of Multitarget Stool DNA Testing Versus One Colonoscopy

2026-02-02 gastroenterology Title + abstract only
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BackgroundSeveral colorectal cancer (CRC) screening modalities are guideline-recommended in the United States, yet they vary considerably in screening interval and real-world adherence. As a result, single-round test performance may not reflect cumulative effectiveness over time. This study compared the 10-year longitudinal outcomes of two CRC screening strategies-- triennial next-generation multitarget stool DNA testing (ng mt-sDNA) and decennial screening colonoscopy. MethodsThis study used t...

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