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APOB to estimated APOB ratio for screening for the APOE2 genotype
2026-01-30
pathology
Title + abstract only
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BackgroundFamilial dysbetalipoproteinemia (FDB) is a genetic lipoprotein disorder that can develop in patients homozygous for the APOE2 genotype ({varepsilon}2/{varepsilon}2). It is associated with decreased clearance of remnant lipoproteins and increased atherosclerotic cardiovascular disease (ASCVD) risk disproportionate to their level of LDL-C. A goal of this study was to develop a screening test for the {varepsilon}2/{varepsilon}2 genotype based on routinely available lipid tests and to dete...
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