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Epigenetic Aging in Monozygotic Twins Exposed to Psychosocial Adversity Suggests Sex-Specific, Contextual Outcomes
2026-01-30
psychiatry and clinical psychology
Title + abstract only
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BackgroundPsychosocial adversity (PSA) contributes to long-term health disparities and increased risk for non-communicable diseases. The effects of PSA arise through complex interactions between genes and the environment, which involve immune, endocrine, and epigenetic dysregulation. MethodsTo examine how adversity affects mental and physical health via epigenetic alterations in a more controlled way, we examined the relationship between PSA and epigenetic aging in 28 monozygotic (MZ) twin pair...
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