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Weight trajectories after last Tirzepatide or Semaglutide prescription across a federated health network
2026-01-28
endocrinology
Title + abstract only
View on medRxiv
Show abstract
GLP-1 receptor agonist (GLP-1RA) discontinuation has been associated with weight regain. However, the real-world association between discontinuation of GLP-1RA prescriptions and weight change has not been explored. We assessed weight trajectories of 4,182 patients in the six months following their last GLP-1RA prescription. Approximately two-thirds of patients showed stable weight or continued weight loss during this period post the last known GLP-1RA prescription. In a representative subset of ...
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