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Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

2026-01-26 public and global health Title + abstract only
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BackgroundIt is critical public health concern to identify safety signals originating from wide-scale immunization efforts. Such safety signals may be identified from spontaneous reports and other data sources. Although some work has been done on the best methods for vaccine safety surveillance, there is a scarcity of information on how these perform in analyses of real-world data. MethodsWe use four administrative claims databases and one electronic health record (EHR) database to evaluate the...

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