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Comparative Effectiveness and Cardiovascular Outcomes of Infliximab reference product and Biosimilars in Patients with Inflammatory Bowel Disease

2026-01-27 gastroenterology Title + abstract only
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BackgroundAnti-tumor necrosis factor (anti-TNF), particularly infliximab, have transformed inflammatory bowel disease (IBD) management, but their high cost imposes a significant economic burden. Infliximab biosimilars were introduced to reduce the unmet needs. Despite the approval of infliximab biosimilars, real-world evidence of cardiovascular safety and effectiveness of infliximab biosimilars is lacking among patients with IBD. In this trial emulation, we compared the effectiveness and cardiov...

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