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Early, Late, & Self-Selected Time-Restricted Eating: Impact on Hepatic Fat, Liver Health, & Fecal Microbiota in Adults with Overweight or Obesity

2026-01-19 endocrinology Title + abstract only
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Background and aimsThe optimal eating window for time-restricted eating (TRE) remains unclear. We investigated the effects of 8-hour TRE combined with usual care (UC, a Mediterranean diet-based education program), versus UC alone over 12 weeks on hepatic fat fraction, liver health markers, and fecal microbiota in adults with overweight or obesity. MethodsIn this multicenter randomized trial, participants (50% women) were assigned to UC (n=49), early TRE (n=49), late TRE (n=52), or self-selected...

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