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Diverging trajectories of cardiorenal protection: from early benefit to late attenuation with multifactorial target achievement across cardiovascular- kidney-metabolic syndrome stages

2026-01-16 nephrology Title + abstract only
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BackgroundThe extent to which achieving multiple metabolic treatment targets confers sustained cardiorenal protection across all stages of cardiovascular - kidney - metabolic (CKM) syndrome remains uncertain. MethodsThis multicenter retrospective cohort study used data from the China Renal Data System (CRDS). Participants were classified into CKM stages 1-4. Metabolic target achievement was defined as simultaneous control of blood pressure (BP<130/80 mmHg), fasting blood glucose (FBG<5.6 mmol/L...

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