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circDiscoverer: A resource for curated and predicted circRNA-Protein interactions with experimental support tools

Srinivasan, S.; Kumar, S.; Chatterjee, S.; Chande, A.

2026-01-09 bioinformatics
10.64898/2026.01.08.698416 bioRxiv
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AbstractCircular RNA (circRNA) interacts with miRNAs and proteins and can regulate various cellular processes. Compared to circRNA-miRNA interaction, circRNA-protein interaction (CPI) has been relatively less explored, following which we developed a comprehensive user-friendly web resource, circDiscoverer, which provides an open-access knowledge base empowering characterization of circRNA-protein interactions in Homo sapiens. circDiscoverer contains manually curated circRNA-protein interactions from published articles and predicted circRNA-protein interactions. Furthermore, the resource offers comprehensive insights into protein binding profiles and presents detailed information on interacting circRNAs, including qRT-PCR primer sequences, guide RNAs, and potential RNA modifications, thereby providing an integrated platform for researchers. circDiscoverer is available at https://aclab.iiserb.ac.in.

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.