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Clinical Relevance of Concomitant Large Artery Steno-occlusion and Risk of Recurrent Stroke in Atrial Fibrillation

2026-01-13 neurology Title + abstract only
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BackgroundRecurrent ischemic stroke remains a major concern in patients with nonvalvular atrial fibrillation (NVAF) despite anticoagulation. However, not all NVAF-related strokes are purely cardioembolic--concomitant large artery steno-occlusion (cLASO) is frequently observed and may represent an independent contributor to stroke recurrence. Current guidelines address these cases but focusing almost exclusively on the cardioembolic source. This approach contrasts sharply with the management of a...

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