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Modeling epidemiological patterns of smallpox in Copenhagen in the 19th century after the introduction of the vaccine

2026-01-06 infectious diseases Title + abstract only
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In 1798, Jenners smallpox vaccine made it possible to prevent the deadliest of childhood diseases. In Denmark the vaccine was used from 1801, and by 1810 a mandatory 1-dose childhood vaccination program was instituted, free of charge. As proof of vaccination (or natural immunity) was required for church confirmation around age 13, about 90 % of children were vaccinated and smallpox disappeared from Copenhagen after 1808. After a 16-year "honeymoon period", it returned in 1824 with a new face: a ...

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