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Immune-inflammatory Indices as Predictors of Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Observational Studies

2026-01-09 surgery Title + abstract only
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BackgroundPathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) for locally advanced rectal cancer (LARC) is associated with improved survival and organ preservation. Available blood-based inflammatory indices may help to predict pCR and guide individualized treatment. MethodsWe conducted a comprehensive search of PubMed, Web of Science, Scopus, and Embase, and Cochrane Library to identify studies including adult patients with pathologically confirmed LARC treated with n...

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