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Assessing the Impact of the Healthy Vaccinee Effect on COVID-19 Vaccine Effectiveness Estimates

2026-01-03 epidemiology Title + abstract only
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BackgroundHealth status influences uptake of COVID-19 vaccination, with vaccinated individuals generally being healthier than their unvaccinated counterparts. However, the extent to which this healthy vaccinee effect biases vaccine effectiveness estimates remains unclear. This study investigated how different levels of the healthy vaccinee effect may impact these estimates. MethodsThree national, matched, retrospective cohort studies were conducted on the population of Qatar from February 5, 20...

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