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Ultrasound-guided skeletal muscle biopsy technique permits measurement of structural, functional, cellular and biochemical properties

2026-01-02 rehabilitation medicine and physical therapy Title + abstract only
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Human muscle biopsies are often required to study or diagnose diseases. However, traditional approaches are challenging due to limited sample size, quality, or patient discomfort. Fine-gauge needle biopsies ([≥]14-gauge), present an alternative but yield insufficient sample sizes for histology or function. Ultrasound guidance, coupled with vacuum-assisted, single needle-insertion multiple sampling addresses these challenges. In 19 healthy participants (mean age: 30.1{+/-}10 years, 42% male), ...

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