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Pancreatic enzymes and/or bile acids for acutely ill severely malnourished children: a double blind randomized placebo-controlled trial

2025-12-29 pediatrics Title + abstract only
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BackgroundTranslocation of bacteria across the intestinal barrier has been postulated to contribute to mortality among severely malnourished children. Pancreatic enzymes (PE) and bile acids (BA) have anti-bacterial properties in the small intestine, but severe malnutrition is associated with impaired exocrine pancreatic and hepatobiliary functions. We evaluated whether ancillary treatment with PE and BA improves survival in hospitalized, acutely ill, severely malnourished children. Methods and ...

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