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Efficacy of the Serogroup B Neisseria meningitidis Vaccine (4CMenB) in Preventing Experimental Neisseria gonorrhoeae Urethral Infection: A Double-Blind Randomized Controlled Human Challenge Study Protocol
2025-12-15
sexual and reproductive health
Title + abstract only
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IntroductionRates of sexually transmitted infections are on the rise globally, including those caused by Neisseria gonorrhoeae. Retrospective analyses across clinical settings around the world have indicated that rates of gonorrhea declined following mass vaccination campaigns vaccines made with outer membrane vesicles (OMV) from Neisseria meningitidis serogroup B, a pathogen closely related to N. gonorrhoeae. The US FDA-approved N. meningitidis serogroup B vaccine (4CMenB) contains N. meningiti...
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