Back

Molecular Screening of Hemoglobin S Variant in Anemia Patients of Eastern UP Population

Rai, V.; Yadav, U.; Kumar, P.

2019-11-04 molecular biology
10.1101/830117 bioRxiv
Show abstract

Hemoglobinopathies are the most common type of inherited disease in human. in India the most frequent and clinically significant hemoglobin structural variants are HbS, HbD and HbE. The HbS mutation, in which a glutamic acid at position 6 in the {beta} chain is substituted for valine Sickle cell disease is a major health problem in some parts of India. 2 ml blood sample was collected from 350 anemia patient and PCR-RFLP method was used for hemoglobin S analysis. Out of 350 samples, in four individuals, HbS mutation was found in homozygous ({beta} 6/{beta} 6) condition. All four individuals are Sickle cell cases. In conclusion, the percentage of Sickle cell disease was observed as 1.14% in Eastern UP anemic patients.

Matching journals

The top 2 journals account for 50% of the predicted probability mass.

1
PLOS ONE
● 5266 papers in training set
Top 1%
47.6%
Similar papers in this journal
2
Molecular Biology Reports
○ 21 papers in training set
Top 0.1%
7.6%
Similar papers in this journal
50% of probability mass above
3
Gene
○ 46 papers in training set
Top 0.1%
7.6%
Similar papers in this journal
4
Scientific Reports
○ 3612 papers in training set
Top 37%
2.8%
Similar papers in this journal
5
F1000Research
○ 88 papers in training set
Top 0.9%
2.2%
Similar papers in this journal
6
Medical Research Archives
● 11 papers in training set
Top 0.1%
2.0%
7
BMC Research Notes
○ 33 papers in training set
Top 0.4%
1.6%
8
Gene Reports
○ 14 papers in training set
Top 0.4%
1.2%
9
Informatics in Medicine Unlocked
○ 22 papers in training set
Top 0.8%
1.2%
10
Heliyon
○ 152 papers in training set
Top 5%
1.2%
11
Journal of Biomolecular Structure and Dynamics
○ 43 papers in training set
Top 0.8%
1.1%
12
Biology Methods and Protocols
◐ 61 papers in training set
Top 2%
1.0%
13
Microbial Pathogenesis
○ 17 papers in training set
Top 0.3%
0.9%
14
BMC Genomics
○ 406 papers in training set
Top 7%
0.9%
15
Frontiers in Public Health
○ 148 papers in training set
Top 6%
0.9%
16
Access Microbiology
● 25 papers in training set
Top 0.9%
0.6%
17
Current Microbiology
○ 18 papers in training set
Top 0.8%
0.6%
18
Journal of Family Medicine and Primary Care
○ 12 papers in training set
Top 0.8%
0.5%
19
PeerJ
◐ 308 papers in training set
Top 13%
0.5%
20
Frontiers in Cellular and Infection Microbiology
○ 109 papers in training set
Top 4%
0.5%
21
Molecular Genetics and Genomics
○ 12 papers in training set
Top 0.3%
0.5%
22
FEBS Letters
○ 47 papers in training set
Top 1%
0.5%
23
Frontiers in Physiology
○ 106 papers in training set
Top 4%
0.5%
24
International Journal of Molecular Sciences
○ 494 papers in training set
Top 19%
0.5%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.