Proliferation in the epiblast-hypoblast layers of the primitive-streak chick embryoblast in response to epidermal growth factor
Cunningham, F. O.
Show abstract
The reaction of twenty four hour old primitive streak chick embryoblasts exposed to epidermal growth factor was compared with non-exposed controls. After 24-36 hours incubation, proliferation up to 5-6 cell layers in thickness of the epiblast-hypoblast layers was evident in the EGF exposed embryo blasts. This compared with the normally expected one cell layer in thickness at this stage of development.
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