Back
#1
18.3%
Top 1%
11.3%
Top 3%
8.0%
Top 2%
6.6%
Top 1%
6.6%
Top 3%
5.2%
Top 62%
4.3%
Top 84%
4.3%
Top 3%
2.9%
Top 3%
2.9%
Top 2%
2.0%
Top 0.9%
2.0%
Top 2%
2.0%
Top 2%
1.6%
Top 1%
1.6%
Top 3%
1.6%
Top 46%
1.4%
Top 3%
1.4%
Top 4%
1.2%
Top 62%
1.0%
Top 2%
1.0%
Top 1%
1.0%
Top 12%
0.7%
Top 4%
0.7%
Top 2%
0.7%
Top 29%
0.7%
Integrating Multi-Ancestry Polygenic Risk Scores and Wearable Data to Detect Depression and Gene-Environment Interactions in Youth
2025-12-01
psychiatry and clinical psychology
Title + abstract only
View on medRxiv
Show abstract
BackgroundDepression (DEP) has an estimated heritability of [~]37%. Polygenic risk scores (PRS), which aggregate common genetic variant effects, account for up to 8.4% variance in case versus control status. Understanding the relationships between sleep, activity, and DEP symptoms, and whether these relationships differ depending on genetic predisposition is crucial for early identification, particularly during adolescence when DEP rates tend to increase. Method2,768 adolescents (African [AFR],...
Predicted journal destinations
1
Journal of Child Psychology and Psychiatry
18 training papers
2
Journal of Affective Disorders
72 training papers
3
Translational Psychiatry
94 training papers
4
Molecular Psychiatry
84 training papers
5
Psychological Medicine
52 training papers
6
Frontiers in Psychiatry
56 training papers
7
Scientific Reports
701 training papers
8
PLOS ONE
1737 training papers
9
Psychiatry Research
33 training papers
10
Biological Psychiatry
36 training papers
11
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
27 training papers
12
Biological Psychiatry Global Open Science
23 training papers
13
BJPsych Open
24 training papers
14
Brain, Behavior, and Immunity
35 training papers
15
The British Journal of Psychiatry
21 training papers
16
Journal of Psychiatric Research
22 training papers
17
Nature Communications
483 training papers
18
Neuropsychopharmacology
29 training papers
19
Schizophrenia Bulletin
21 training papers
20
BMJ Open
553 training papers
21
Neuroscience & Biobehavioral Reviews
19 training papers
22
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
15 training papers
23
NeuroImage: Clinical
77 training papers
24
BMC Psychiatry
20 training papers
25
BMJ Mental Health
15 training papers
26
JAMA Network Open
125 training papers