Clinico Etiological Profile Of Urinary Tract Infection And Urolithiasis

BACKGROUNDThe prevalence of urolithiasis in the general population has increased worldwide in the past decades. The aim of this study is to investigate the bacteriological profile of urine samples from patients with kidney stones. By analyzing the bacteria present in the urine, we can gain insights into potential associations between specific types of stones and the microbial flora. This information can be crucial for tailoring treatment strategies, including antibiotic therapy and preventive measures. METHODOLOGYIt is a retrospective cross-sectional study comprised of all patients who were diagnosed with urolithiasis at Ramaiah Memorial Hospital, Bengaluru, Karnataka. In this study we assessed a total of 235 patients who were admitted to our hospital due to kidney stones. The socio-demographic and epidemiological profile. Type of calculus, urinalysis and treatment method was considered. RESULTSOut of 235 patients, 189 (80.4%) were males, and 46 (19.6%) were females. 80 patients (34% of the total patients) were found to have clinical or laboratory evidence of urinary tract infection (UTI). Most common organism isolated was Escherichia coli in 19 patients (48.7%) followed by Klebsiella in 15 patients (38.46%). In biochemical analysis most common type of stone found was calcium oxalate monohydrate (97.43%) and calcium oxalate dihydrate (66.66%). CONCLUSIONPositive urine culture in stone formers should not be assumed to indicate purely infection-related stones; metabolic evaluation remains essential. In patients with recurrent CaOx stones and persistent bacteriuria, targeted antibiotic therapy and biofilm-disrupting strategies could be considered to reduce recurrence.