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Exploring the Causal Relationship Between Body Mass Index and Kidney Function Using Tissue-Partitioned Mendelian Randomization
2025-08-21
nephrology
Title + abstract only
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BackgroundChronic kidney disease (CKD) represents a leading non-communicable disease, significantly contributing to global morbidity and mortality. Mendelian randomization studies (MR) have been integral in providing robust evidence that increased body mass index (BMI) has a causal impact on CKD. However, dissecting which specific mechanisms are primarily responsible for disease development remains challenging. ObjectiveTo explore whether the effects of BMI to kidney function are driven primari...
Predicted journal destinations
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Journal of the American Society of Nephrology
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