The Urban Divide: Socioeconomic Status and Its Impact on Cancer in the Age of Urbanization
Koyanagi, Y. N.; Kawaura, M.; Matsuo, K.; Kawakatsu, Y.; Taniyama, Y.; Oze, I.; Otani, T.; Takahashi, K.; Yamaguchi, R.; Nakaya, T.; Ito, H.
Show abstract
Against accelerating global urbanization, we analyzed regional cancer health disparities in Japan using nationwide cancer incidence and mortality data. This cross-sectional ecological study included 1889 Japanese municipalities, categorized as urban, suburban, and rural. Using 2015 Census data, we estimated the normalized Areal Deprivation Index (normADI) and, using 2016-2018 cancer registry and vital statistics data, estimated standardized incidence and mortality ratios with a fully Bayesian hierarchical spatial model (FBSIR/FBSMR). We examined their association by urbanicity, analyzing 3,056,535 incident cases and 1,140,250 deaths. Higher normADI was associated with increased FBSMR for all cancers, particularly in urban areas (risk ratio 1.18 for males; 1.12 for females). Mortality of stomach, colorectal, lung, and liver cancers increased with increasing deprivation in urban areas, with stronger effects for male colorectal, liver, and lung cancers as urbanicity increased. Sensitivity analyses using alternative modeling formulations, both spatial and non-spatial, yielded broadly similar results. The greater impact of ADI on cancer mortality in urban areas underscores the need for poverty-focused cancer prevention strategies with growing urban populations.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Epidemiological characteristics and transmission dynamics of the outbreak caused by the SARS-CoV-2 Omicron variant in Shanghai, China: a descriptive study 91%
- Long-term PM 2.5 exposure and depressive symptoms in China: a quasi-experimental study 90%
- Comparison of control and transmission of COVID-19 across epidemic waves in Hong Kong: an observational study 89%
Similar papers in this journal
- Area-based socioeconomic inequalities in cancer mortality in Germany – widening, narrowing or reversing inequalities between 2003 and 2019? 93%
- Digitalization impacts the COVID-19 pandemic and the stringency of government measures 91%
- Individual’s daily behaviour and intergenerational mixing in different social contexts of Kenya 90%
Similar papers in this journal
- Ecological Analysis of the Temporal Trends in the Association of Social Vulnerability and Race/Ethnicity with County-Level COVID-19 Incidence and Outcomes in the United States 91%
- Factors Associated with Serious Psychological Distress during the COVID-19 Pandemic in Japan 90%
- Social disparities in the first wave of COVID-19 infections in Germany: A county-scale explainable machine learning approach 90%
Similar papers in this journal
- Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures 89%
- Analytical and clinical validation of a circulating tumor DNA-based assay for multi-cancer early detection 88%
- Risk of cancer in regular and low meat-eaters, fish-eaters, and vegetarians: a prospective analysis of UK Biobank participants 88%
Similar papers in this journal
- Characteristic spatial scales of SARS-CoV-2 pandemics: lessons from mass rapid antigen testing in Slovakia 89%
- Association between City-wide Lockdown and COVID-19 Hospitalization Rates in Multigenerational Households in New York City 89%
- Identification of cuproptosis and ferroptosis-related subtypes and development of a prognostic signature in colon cancer 89%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.