Back

SVEP1 Upregulation Is a Prominent Molecular Response to Dietary Sodium Loading and Correlates with Inverse Salt Sensitivity

2025-08-14 cardiovascular medicine Title + abstract only
View on medRxiv
Show abstract

BackgroundWhile some individuals exhibit salt sensitivity, others demonstrate salt resistance or inverse salt sensitivity--blood pressure reduction during high sodium intake. The molecular mechanisms underlying heterogeneous blood pressure responses to dietary sodium remain poorly understood. Deep proteomics provides a new tool to identify molecular mediators of salt resistance and inverse salt sensitivity. MethodsWe conducted a randomized crossover trial in 20 normotensive adults comparing 8-d...

Predicted journal destinations