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Levels of evidence supporting recommendations in clinical practice guidelines: meta-epidemiological study
Boesen, K.; Klingenberg, S.; Gluud, C.
2025-08-13
epidemiology
10.1101/2025.08.11.25333132
medRxiv
Show abstract
In this research letter, the levels of evidence supporting recommendations in clinical practice guidelines is assessed. It is a meta-epidemiological study of large-scale guideline assessments.
Matching journals
●Non-profit
◐University press
○Commercial
The top 8 journals account for 50% of the predicted probability mass.
1
Journal of Clinical Epidemiology
○
31 papers in training set
Top 0.1%
15.5%
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2
BMJ Open
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601 papers in training set
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10.0%
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3
PLOS ONE
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6.4%
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4
Research Synthesis Methods
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20 papers in training set
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5.3%
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5
Pharmacoepidemiology and Drug Safety
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18 papers in training set
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4.4%
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50% of probability mass above
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.