Feline leukaemia virus subgrouping using the viral interference assay
Abdillah, D. A.; Hiratsuka, T.; Matsuyama, F.; Hattori, Y.; Soma, T.; Shimoda, T.; Kato, T.; Sakai, H.; Hisasue, M.; Miyake, A.; Nishigaki, K.
Show abstract
Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated de novo. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of cases, whereas co-infection with both FeLV-A and FeLV-B was observed in 62% of cases. No cases of FeLV-B infection alone were observed. Cases of co-infection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The X region containing FeLV was discovered in two new cases. This study may elucidate the mechanism underlying FeLV-B-induced diseases.
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