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Genetic Factors and the Outcomes of Transplant-Associated Thrombotic Microangiopathies

2025-07-11 hematology Title + abstract only
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Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe endothelial complication following allogeneic hematopoietic stem-cell transplantation (allo-HSCT), associated with high mortality when not promptly diagnosed and treated. This study aimed to delineate the genetic landscape associated with TA-TMA and assess its impact on clinical outcomes. We retrospectively analyzed 1069 allo-HSCT recipients between January 2016 and May 2020, identifying 131 patients who met diagnostic criteri...

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