Evaluation of the SEIMC score as a death predictor of SARS-CoV-2 pneumonia in vaccinated patients: a validation cohort
Gil-Rodriguez, J.; Aranda-Laserna, P.; Montero-Alonso, M. A.; Martinez de Victoria Carazo, J.; Fernandez Reyes, D.; Guirao-Arrabal, E.
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IntroductionThis is a single-centre prospective cohort study to validate the Spanish Society of Infectious Diseases and Microbiology (SEIMC) score for predicting 28-days mortality in vaccinated patients with SARS-CoV-2 pneumonia. MethodsWe included 127 adult patients with confirmed SARS-CoV-2 infection by polymerase chain reaction (PCR) admitted to the hospital ward. Among them, 92 were unvaccinated, 17 one-dose vaccinated and 18 two-doses. The SEIMC score was calculated at admission, and we analysed its correlation with 28-days mortality. ResultsWe found significant differences between the number of vaccinations according to the SEIMC score classification. The SEIMC score and 28-days mortality were significantly correlated in the whole cohort (p=0.001), in unvaccinated patients (p=0.001) and in those with some vaccine doses (p=0.003) or two-doses (p = 0.005), but not in one-dose vaccinated patients (p=0.235). ConclusionThe SEIMC score remains a useful scale for predicting 28-day mortality in vaccinated patients.
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