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Preliminary results of a randomized controlled trail: Effects of remotely supervised physical activity on health profile in frail older adults

Zhang, X.; Li, F.; Li, J.; Bai, X.

2025-07-01 geriatric medicine
10.1101/2025.06.26.25330386 medRxiv
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IntroductionSupervised physical activity (PA) interventions have demonstrated efficacy and safety in improving health outcomes among frail populations. However, the growing disparity between limited healthcare resources and the rapidly aging population poses a significant challenge. Remotely delivered PA interventions may offer a viable solution for resource-limited regions. This study presents preliminary findings from a pre-designed protocol, examining the health benefits of a remotely supervised PA intervention, with a focus on frailty components. MethodsParticipants aged [&ge;]65 years with a FRAIL score [&ge;]3 were enrolled. The intervention group (IG) received a progressive PA program delivered via a WeChat-based application, along with smart insole-equipped sports shoes to monitor PA. The control group (CG) received routine care. The primary outcome was physical function, assessed via the Timed Up & Go (TUG) test; secondary outcomes included self-reported and objective measures. Assessments were conducted at baseline and 12 weeks post-intervention. ResultsOf the 20 participants enrolled (mean age 69 {+/-} 5.73 years; 75% female), 3 withdrew. Baseline characteristics did not differ significantly between groups. Post-intervention, no significant between-group difference was observed in TUG (IG: 12.03 {+/-} 0.39 vs CG:13.72 {+/-} 0.85; p = 0.07). Generalized Estimating Equation (GEE) analysis confirmed a significant reduction in and FRAIL score (IG: 1.56 {+/-} 0.23 vs CG: 2.88 {+/-} 0.21; p < 0.001) for the IG. DiscussionThe 12-week remotely supervised PA intervention significantly improved frailty and physical performance but did not enhance psychological or cognitive function. Future large-scale studies are needed to comprehensively evaluate effectiveness, particularly long-term outcomes.

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