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The Generational Health Drift: A Systematic Review of Evidence from the British Birth Cohort Studies

Gimeno, L.; Moreno-Agostino, D.; Danka, M.; Guo, Y.; Goisis, A.; Dowd, J. B.; Ploubidis, G. B.

2025-06-12 epidemiology
10.1101/2025.06.12.25329414 medRxiv
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BackgroundLife expectancy improved dramatically during the 20th century. Whether more recent generations are also living longer in good health has serious implications for healthcare systems and the economy. AimTo synthesise evidence on cohort differences in physical and mental health from the British birth cohort studies, born 1946 to 2000-02. MethodElectronic databases (MEDLINE, EMBASE, PsycInfo, Web of Science, up to 25 June 2024) were searched for pairwise combinations of the six cohort studies of interest or for terms indicating the use of at least two cohorts in the same study. Articles were eligible for inclusion if they compared the health of two or more included cohorts at similar ages (within 3 years). ResultsResults were summarised narratively. There was little evidence for improving health across successive cohorts born since 1946 when compared at the same age. For several outcomes - particularly obesity, mental ill-health and diabetes - prevalence of poor health was higher in more recent generations, a pattern we term "Generational Health Drift". Many outcomes were self-reported, but studies using observer-measured outcomes (anthropometric measures and blood biomarkers) tended to support conclusions based on self-reports. ConclusionMore research is needed to understand the drivers of this trend, shaped by changing exposure to preventable social and environmental risk factors across the lifecourse, and to monitor future trends in disability and functional limitation. The Generational Health Drift has serious implications for policy, planning, and funding allocation to be able to support a growing number of people living with chronic health conditions.

Published in Population Studies · not in our set (fewer than 10 published preprints to learn from) · training set

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