Stool Genomics for Enhanced Monitoring of Nutrition Interventions in Childhood Malnutrition
Aqeel, A.; Iqbal, N. T.; Soomro, S. I.; Ahmed, S.; McDonald, T. K.; Osborne, O.; Jiang, S.; Ives, N.; Ahsan, K.; Umrani, F.; Barratt, M. J.; Gordon, J. I.; Ali, S. A.; David, L. A.
Show abstract
Ready-to-use therapeutic and supplementary foods (RUTF/RUSF) are a primary treatment for childhood malnutrition, but measuring intervention compliance is labor intensive. We applied FoodSeq, a fecal genomic dietary assessment biomarker, in malnourished infants (3-15 months) from Matiari, Pakistan. FoodSeq identified a significant spike in chickpea, a primary RUSF ingredient, during RUSF administration, highlighting the potential of genomics as an empirical tool for compliance monitoring and dietary analysis in community-based malnutrition programs.
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