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Epigenetic mediation may explain intergenerational associations between maternal lifestyle and birth weight of offsprings - Findings from the NorthPop prospective birth cohort

2025-06-01 genetic and genomic medicine Title + abstract only
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BackgroundEpigenetic alterations during fetal development have been proposed as key factors explaining associations between maternal lifestyle during pregnancy and later health outcomes in the offspring, pertaining to the developmental origin of health and disease (DOHAD) hypothesis. ObjectivesTo assess the association of maternal lifestyle with offsprings birth weight and underlying epigenetic mediatory mechanisms in the NorthPop prospective birth cohort. MethodsA three-step analytic pipeline...

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