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Remodeling of human diurnal adipose tissue transcriptome by the composition of morning and afternoon meals
2025-05-15
nutrition
Title + abstract only
View on medRxiv
Show abstract
The timing of carbohydrate and fat intake modulates the metabolic status, yet the underlying mechanisms in humans remain poorly understood. In this crossover trial, we investigated the effects of two isocaloric 4-week dietary patterns - high carbohydrate in the morning and high fat in the afternoon (HC/HF) and the reverse (HF/HC) - on the subcutaneous adipose tissue (SAT) transcriptome in non-diabetic men. Analysis of SAT samples collected across the day identified 1386 genes exhibiting diurnal ...
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