Effectiveness of therapeutic exercise in patients with fibromyalgia on psychosocial and clinical outcomes: a systematic review protocol
Enea, G.; Ginestra, A.; Fiolo, R.; Brighina, F.; Piampiano, F.; Tarantino, C.; Notararigo, E.; Assanto, G.
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BackgroundFibromyalgia (FMS) is a chronic syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and psychological symptoms such as anxiety and depression (1). Therapeutic exercise is recommended as a non-pharmacological treatment for FMS management; however, its effectiveness on clinical and psychosocial parameters remains uncertain (2). This systematic review aims to synthesize the available evidence on the impact of therapeutic exercise in patients with FMS, assessing both clinical outcomes (pain, physical function) and psychosocial outcomes (quality of life, psychological well-being). MethodsThis review will include randomized controlled trials (RCTs) published between 2014 and 2024 that evaluate the effectiveness of therapeutic exercise in adult patients with FMS. A comprehensive literature search will be conducted in PubMed, PEDro, Embase, and Cochrane CENTRAL using predefined search strategies. Study selection will follow a blinded process conducted by two independent reviewers, with any disagreements resolved by a third reviewer. Data will be extracted and synthesized into tables and descriptive summaries, without the use of inferential statistical methods or meta-analysis. Ethics and DisseminationAs this is a systematic review, ethical approval is not required. The results will be disseminated through publications in peer-reviewed journals and presentations at national and international scientific conferences, with the aim of supporting clinical practice and research in FMS management.
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