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Self-paced silent speech brain-computer interface for device control

Luo, S.; Angrick, M.; Coogan, C.; Candrea, D. N.; Wyse-Sookoo, K.; Schippers, A.; Ganji, R.; Milsap, G. W.; Anderson, W. S.; Gordon, C. R.; Tippett, D. C.; Maragakis, N. J.; Clawson, L. L.; Vansteensel, M. J.; Tenore, F. V.; Hermansky, H.; Fifer, M. S.; Ramsey, N. F.; Crone, N. E.

2025-04-10 neurology
10.1101/2025.04.09.25325542 medRxiv
Show abstract

Brain-computer interfaces can potentially restore autonomy to people with paralysis, including the ability to control their own environment via smart devices in the home. BCI applications for controlling smart devices to date have required visual displays or auditory cues, limiting the users ability to autonomously and privately issue commands. In this study, a clinical trial participant with amyotrophic lateral sclerosis (ALS) used a chronically implanted electrocorticographic (ECoG) BCI to control smart devices with self-paced silent speech commands. Across 18 experimental sessions, silently mimed speech commands were detected in real time and decoded with a median accuracy of 97.1% (chance: 7.14%). These results demonstrate that silently attempted speech can be reliably decoded without exogenous timing cues, supporting the feasibility of reliable autonomous smart device control with an implantable BCI.

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