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Ocular Manifestations in a Cohort of Patients with Mpox in the Democratic Republic of the Congo 2007 - 2011

Placide, M.-K.; Nguyen, N. V.; Mwanza, J.-C.; Carag, J.; Linderman, S.; Fashina, T.; Kinganda Lusamaki, E.; Wawina-Bokalanga, T.; Aziza, A.; Makangara-Cigolo, J.-C.; Hasivirwe Vakaniaki, E. V.; Anta, Y.; Yango, J.; Tshiani, O.; Kindrachuk, J.; Liesenborghs, L.; Peeters, M.; Delaporte, E.; Rimoin, A. W.; Huggins, J. W.; Riu-Rovira, T.; Ahuka, S. M.; Martin, J. W.; Crozier, I.; Yeh, S.; Muyembe, J.-J. T.

2025-04-09 ophthalmology
10.1101/2025.04.07.25325069 medRxiv
Show abstract

This report describes the ocular manifestations in a cohort of patients with Clade I mpox evaluated in the Democratic Republic of the Congo (DRC) from 2007 to 2011, as well as the clinical course of a pediatric patient with mpox associated with ocular disease. Among 216 patients, ocular manifestations were observed in 8.3% of the patients, including conjunctivitis, eyelid lesions, eyelid swelling, eye pain, orbital swelling, keratitis, and corneal staphyloma. These findings highlight the broad spectrum of ocular manifestations with potential sight-threatening consequences in patients with mpox.

Published in ASM Case Reports · not in our set (fewer than 10 published preprints to learn from) · training set

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