Projections of the impact of transmission-reducing pediatric influenza vaccine in South Africa using high resolution immunologic and infection data

2025-04-04 infectious diseases Title + abstract only

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BackgroundTraditional influenza vaccination programs focus on preventing severe illness through the vaccines direct effect. However, vaccinating children may substantially reduce overall burden by lowering transmission, especially in high infection settings and when effective transmission reducing vaccines become available. MethodsTo evaluate the impact of a transmission-reducing vaccination campaign, we developed a Susceptible-Latent-Infectious-Recovered (SLIR) compartmental transmission model...

Projections of the impact of transmission-reducing pediatric influenza vaccine in South Africa using high resolution immunologic and infection data

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