Complement and coagulation cascade crosstalk in endometriosis and the potential of JAK inhibitors - a network meta-analysis

2025-03-25 obstetrics and gynecology Title + abstract only

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BackgroundLack of knowledge on the processes driving endometriosis hinders early detection and therapy development. Our purpose was to identify key molecular events involved in lesion formation across diverse populations and to detect transcriptomic changes in eutopic endometrium that accompany endometriosis. MethodsWe searched Gene Expression Omnibus and ArrayExpress and performed differential gene expression analysis and a network meta-analysis on nine qualifying datasets. Those contained tra...

Complement and coagulation cascade crosstalk in endometriosis and the potential of JAK inhibitors - a network meta-analysis

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