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Approaches for Interchannel EEG Analysis

van Drongelen, W.; Nordli, D. R.; Taha, M.; Nordli, D. R.

2025-02-28 neurology
10.1101/2025.02.27.25323027 medRxiv
Show abstract

Here, we present a novel analysis pipeline for scalp EEG signals. With our approach, we focus on the interchannel relationships using standard correlation techniques in the spatiotemporal and frequency domains as well as a recently developed triple correlation-based analysis. Since we compute correlations in multichannel EEG data, we employ (non-standard) bipolar montages with non-overlapping electrode positions to avoid montage-induced correlations in space-, time- and frequency domains. In addition to the correlation studies, we determine the EEG frequency components, phase-amplitude coupling and a burst index. The procedures are tested with simulated signals and illustrated with results obtained from a small patient group.

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