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State of health of the gut microbiome assessed through a quantitative metabolomic-based marker panel

2025-02-18 gastroenterology Title + abstract only
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Defining the "health" of the gut microbiome or microbial organ has been elusive and controversial. This in turn makes defining gut dysbiosis (imbalances in gut microbiota) an enigma particularly in determining what, how, and when to intervene to restore eubiosis. Taxonomical profiles of gut microbiota have typically been used but are unreliable because of highly variable interindividual taxa and arbitrary functional assignments generalized to microbial groups. We therefore developed a functional...

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