Modelling and simulation of the interactions between the cardiovascular system, VA ECMO and IABP: when is it an appropriate combination?
De Lazzari, B.; Capoccia, M.; Badagliacca, R.; Maybauer, M. O.; De Lazzari, C.
Show abstract
Veno-arterial extracorporeal membrane oxygenation (VA ECMO) for the management of refractory cardiogenic shock (CS) has been widely used in recent years. Increased left ventricular (LV) afterload induced by retrograde flow remains a limiting factor, which is particularly evident during peripheral VA ECMO support. The concomitant use of the intra-aortic balloon pump (IABP) is an established strategy to achieve LV unloading during VA ECMO support. Nevertheless, there remains controversy about the combined use of IABP during central or peripheral VA ECMO in terms of beneficial effects and outcome. We developed a simulation setting to study left ventricular unloading with IABP during peripheral and central VA ECMO using CARDIOSIM(C), an established software simulator of the cardiovascular system. The aim was to quantitatively evaluate potential differences between the two VA ECMO configurations and ascertain the true beneficial effects compared to VA ECMO alone.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- A coupled atrioventricular-aortic setup for in-vitro hemodynamic study of the systemic circulation: Design, Fabrication, and Physiological relevancy 96%
- Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation: A finite element modeling study. 95%
- Ventricular anatomical complexity and gender differences impact predictions from computational models 94%
Similar papers in this journal
- Hemodynamics Indicates Differences Between Patients With And Without A Stroke Outcome After Left Ventricular Assist Device Implantation 96%
- Biomechanical stress analysis of Type-A aortic dissection at pre-dissection, post-dissection, and post-repair states 96%
- Deployment of a digital twin using the coupled momentum method for fluid-structure interaction: a case study for aortic aneurysm 95%
Similar papers in this journal
- Switching the left and the right hearts: A novel bi-ventricle mechanical support strategy with spared native single-ventricle 98%
- Quantitative Assessment of Aortic Hemodynamics for Varying Left Ventricular Assist Device Outflow Graft Angles and Flow Pulsation 96%
- Effect of Sinotubular Junction Size on TAVR Leaflet Thrombosis: A Fluid-structure Interaction Analysis 96%
Similar papers in this journal
- Machine Learning prediction of cardiac resynchronisation therapy response from combination of clinical and model-driven data 94%
- A compact multifunctional model of the rabbit atrioventricular node with dual pathways 94%
- Predictive modeling of secondary pulmonary hypertension in left ventricular diastolic dysfunction 93%
Similar papers in this journal
- Experiments and Simulations to Assess Exercise-Induced Pressure Drop Across Aortic Coarctations 95%
- Remodeling-mediated changes in left ventricular mechanics under settings of chronic pressure overload and exercise 92%
- Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation 90%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.