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Coxsackievirus A24 variant whole genome sequencing from clinical samples using a three overlapping amplicons strategy

Morobe, J. M.; Odoyo, S.; Lambisia, A. W.; Moraa, E.; Houldcroft, C. J.; Ochola-Oyier, L. I.; Holmes, E. C.; Githinji, G.; Agoti, C. N.

2025-01-16 infectious diseases
10.1101/2025.01.16.25320645 medRxiv
Show abstract

We developed a whole genome sequencing assay for coxsackievirus A24 variant (CA24v), a major cause of acute hemorrhagic conjunctivitis, and used it to recover three near complete genomes from the 2024 CA24v outbreak in Kenya. This assay will support studies on CA24v genomic epidemiology and evolution across Africa.

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