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Sexual dimorphism in human muscle ageing

2025-01-06 geriatric medicine Title + abstract only
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Primary sarcopenia is a progressive, age-related decline of skeletal muscle strength, size, and quality, the socio-economic and health impacts of which are set to increase due to global ageing. Despite differences in the physiology of female and male skeletal muscle being well characterised, their alteration with age is less clear. Here we report a striking sexual dimorphism in arm muscle ageing in 478,438 UK Biobank participants aged 40-82 yr. Although the sex difference in age-related arm musc...

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