Predictors and outcome of post-stroke depression among adults admitted for first stroke at referral hospitals in Dodoma, Tanzania: a protocol for a prospective longitudinal observational study

BackgroundSurvivors of strokes are prone to disabilities, especially in underdeveloped countries. Post-stroke depression (PSD) is a common neuropsychiatric condition that exacerbates symptoms and raises the danger of stroke recurrence, disability, and mortality. Nevertheless, little is documented about PSDs incidence, predictors, and consequences. This study aims to assess predictors and outcomes of post-stroke depression among patients admitted with the first stroke episode at referral hospitals in Dodoma, Tanzania. Methods and analysisThe study is a prospective longitudinal observational design; a consecutive sampling technique will be used to attain the estimated sample size. Adults aged [≥]18 years who have had their first stroke episode, within 14 days, and the stroke diagnosis will be verified through brain imaging using CT or MRI. The study will be conducted at referral hospitals in Dodoma region, Tanzania. At admission, baseline clinical parameters will be recorded, and PSD will be evaluated at one and three months after a stroke. Data will be summarised using descriptive statistics; continuous data will be reported as mean (SD) or median (IQR) while categorical data as frequencies and proportions. The PSD predictors will be determined using logistic regression analysis. The study will adhere to data-sharing guidelines and take ethical considerations into account. Ethics and disseminationThe University of Dodomas institutional Research Review and Ethical Committee has granted permission to conduct the study with reference number MA.84/261/02. The relevant authorities granted approval for the study to be carried out at DRRH and BMH.