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The exploration of the characteristics of lower extremity deep venous thromboembolism in patients at admission to a tertiary general hospital in a fourth-tier city in China

Pan, J.; Sun, J.; Song, J.; Fu, G.; Lei, Y.; Wang, L.

2024-12-13 health informatics
10.1101/2024.12.12.24318933 medRxiv
Show abstract

With the acceleration of the pace of life and the change of peoples living and working habits, the incidence of venous diseases of lower extremity remains high, and even shows an upward trend year by year, which has a great impact on the quality of life and work efficiency of patients. Well, the occurrence and development of lower extremity deep vein thrombosis (LEDVT) is also related to the economic and humanistic characteristics of a certain place. ObjectivesThe purpose of this paper is to retrospectively analyze the medical records of DVT patients in a general hospital of a fourth-tier city in China, and find some noteworthy characteristics, so as to provide some objective evidence for the diagnosis of DVT in similar hospitals. MethodsAdult patients with central LEDVT with or without pulmonary embolism (PE) were retrospectively analyzed. The general condition, concomitant diseases, laboratory tests and other clinical characteristics were analyzed. ResultsA total of 100 patients medical records were analyzed. The age was non-normally distributed (p =0.004), which from 31 to 87 (65.3{+/-}11.5) years, and 58% of them were 65 years or older. Males (56%) were slightly more than females. Ninety of ninety-four patients D-dimer [≥]1gDDU/ml. Fifty-eight were definitely diagnosed with central LEDVT at admission, of which twenty-three were confirmed as PE by CT. Thirty-five patients with leg symptoms, thirty-three patients with chest symptoms, only two patients had both leg and chest symptoms, and thirty-four patients without any obvious symptoms of DVT when they were admitted to the hospital. Only twelve patients were admitted only with LEDVT, and most of the other patients were complicated with other system/organ diseases. ConclusionsLEDVT is more common in elderly patients aged [≥] 65 years. However, the incidence of patients [≥]75 years old observed in this study may be limited by the local economic situation and life expectancy. The symptoms can present as many, may be the typical leg symptoms, progression to PE may involve chest symptoms, or it may be neither leg symptoms nor chest symptoms that are masked by the symptoms of other concomitant diseases. LEDVT can be complicated with multiple system/organ diseases. It is necessary to screen for DVT in patients with abnormal D-dimer.

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