Back

Searching for Jouvence SnoRNA in the Horse Genome

Peffers, M. J.; Akker, G. V. d.; Clarke, E.; Fang, Y.

2024-11-21 molecular biology
10.1101/2024.11.21.624650 bioRxiv
Show abstract

In humans, various pathologies have been associated with snoRNAs. Others have shown that the expression of a non-canonical snoRNA Jouvence is involved in lifespan determination in relation to gut homeostasis. As snoRNAs are evolutionary conserved, both structurally and functionally, a jouvence orthologue has been identified in humans. This study aimed to locate the Jouvence snoRNA in the horse genome. Using our previous snoRNA data in ageing equine cartilage along with equine genome data we identified a putative equine Jouvence snoRNA gene. ECABCGRLG0000000730 was the primary candidate horse Jouvence snoRNA. The expression of equine Jouvence snoRNA was increased in ageing equine cartilage.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
PLOS ONE
● 5266 papers in training set
Top 10%
18.6%
Similar papers in this journal
2
Gene
○ 46 papers in training set
Top 0.1%
7.9%
Similar papers in this journal
3
Genes
○ 144 papers in training set
Top 0.2%
6.8%
Similar papers in this journal
4
Gene Reports
○ 14 papers in training set
Top 0.1%
6.3%
Similar papers in this journal
5
Molecular Biology Reports
○ 21 papers in training set
Top 0.1%
5.5%
6
Informatics in Medicine Unlocked
○ 22 papers in training set
Top 0.1%
5.5%
Similar papers in this journal
50% of probability mass above
7
BMC Genomics
○ 406 papers in training set
Top 1%
4.3%
8
International Journal of Molecular Sciences
○ 494 papers in training set
Top 4%
3.2%
9
F1000Research
○ 88 papers in training set
Top 0.8%
2.5%
10
Biology Methods and Protocols
◐ 61 papers in training set
Top 0.5%
2.4%
11
Scientific Reports
○ 3612 papers in training set
Top 45%
2.1%
12
BMC Bioinformatics
○ 457 papers in training set
Top 4%
2.0%
13
PeerJ
◐ 308 papers in training set
Top 4%
1.9%
14
BMC Cancer
○ 67 papers in training set
Top 1%
1.7%
15
Heliyon
○ 152 papers in training set
Top 4%
1.5%
16
RNA Biology
○ 78 papers in training set
Top 0.7%
1.5%
17
Genomics
○ 64 papers in training set
Top 1%
1.3%
18
Computational and Structural Biotechnology Journal
● 242 papers in training set
Top 5%
1.1%
19
Frontiers in Genetics
○ 230 papers in training set
Top 4%
1.1%
20
Biochimie
○ 25 papers in training set
Top 0.5%
1.1%
21
BMC Research Notes
○ 33 papers in training set
Top 0.7%
1.1%
22
Viruses
○ 332 papers in training set
Top 4%
0.8%
23
NAR Genomics and Bioinformatics
◐ 242 papers in training set
Top 4%
0.8%
24
Biochemical and Biophysical Research Communications
○ 84 papers in training set
Top 3%
0.6%
25
Medical Research Archives
● 11 papers in training set
Top 0.6%
0.6%
26
Computational Biology and Chemistry
○ 28 papers in training set
Top 1%
0.6%
27
Biochemistry and Biophysics Reports
○ 30 papers in training set
Top 2%
0.6%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.