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Liberality is More Explainable than PCA of Transcriptome for Vertebrate Embryo Development

Ogata, N.

2024-09-24 bioinformatics
10.1101/2024.09.19.613970 bioRxiv
Show abstract

Dimensional reduction approaches of genome scale data are widely used. Liberality is one of the approaches which is a quantitative index of cellular differentiation and dedifferentiation. Here, we analyzed a trend of liberality of time course transcriptome data on vertebrate embryo development. Historically annotated embryo developmental stages matched changes in the trend of liberality. Analyzing liberality of various biological phenomena would be beneficial.

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