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Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model

Yi, Y.; Yan, Y.; Liu, G.; Cui, C.; Zhai, Y.; Xu, K.; He, X.

2024-09-16 physiology
10.1101/2024.09.10.612372 bioRxiv
Show abstract

Psoriasis is an immune mediated, chronic inflammatory skin disease. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have inherent immunomodulatory potency from their parental cells, the mesenchymal stem cells (MSCs). In this study, we revealed the application potential of MSC-EVs to alleviate psoriatic symptoms in imiquimod-induced psoriasis mouse model.

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