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Efficient molecular mendelian randomization screens with LaScaMolMR.jl

2024-08-30 genetic and genomic medicine Title + abstract only
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SummaryThe ever-growing genetic cohorts lead to an increase in scale of molecular Quantitative Trait Loci (QTL) studies, creating opportunities for more extensive two samples Mendelian randomization (MR) investigations aiming to identify causal relationships between molecular traits and diseases. This increase led to the identification of multiple causal candidates and potential drug targets over time. However, the increase in scale of such studies and higher dimension multi-omic data come with ...

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