Novel non-invasive physical photobiomodulation can treat congenital colour vision deficiency and enhance color vision recognition ability: a randomized, single blind, controlled clinical trial
Bao, N.; Jia, L.
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BackgroundColor vision deficiency (CVD) is a common congenital ophthalmic disease, and there are no effective therapeutic measures currently available for this patient population. This study aimed to explore the efficacy of photobiomodulation (PBM) in CVD patients. MethodsA randomized controlled trial design was applied in this study, whereby 80 patients with red-green CVD were randomly divided into PBM treatment and control groups. Color vision was assessed after 1, 2 and 4 weeks of treatment. Statistical analysis of treatment was carried out using the Kruskal-Wallis test with Dunns test for multiple comparisons using SPSS and R software. FindingsCompared to the control group, the color vision of CVD patients exhibited a significant improvement in the PBM treatment group for different parameters (Ps{square}0.05). InterpretationPBM therapy could significantly improve color vision in patients with congenital CVD, especially in patients with green CVD.
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